Home/Alkyl halides
SN1 & SN2
Question#1
In SN1 reaction the correct order of reactivity of alkyl halides is [MDCAT2023]
for SN1/E1 primary < secondary < tertiary due to formation of carbocation.
for SN2/E2 primary > secondary > tertiary
Question#2
SN2 is best carried out with NUMS2015
Question#3
Reaction of alkyl halide with ammonia is called ETEA2010
Hoffman reaction
\( CH_3-CH_2-Br + NH_3 \rightarrow CH_3-CH_2-NH-CH_2-CH_3 \)
\( CH_3-CH_2-Br + CH_3-CH_2-NH-CH_2-CH_3 \rightarrow CH_3-CH_2-N<_{CH_2-CH_3}^{CH_2-CH_3} \)
\( CH_3-CH_2-Br + CH_3-CH_2-N<_{CH_2-CH_3}^{CH_2-CH_3} \rightarrow [_{CH_3-CH_2}^{CH_3-CH_2} >N<_{CH_2-CH_3}^{CH_2-CH_3}]^+Br^- \)
Question#4
Which of the following compound comparatively would react rapidly in an SN2 reaction ETEA2011
Reactivity order ( 1o > 2o > 3o )
Question#5
Displacement reaction that proceed by the SN2 mechanism are most successful with compounds that are ETEA2010
D) Primary compounds with no branch at B-Carbon: less hinderance for nu- to reach at electropositive C.
Question#6
Which of the following reaction show nucleophilic substitution of alkyl halide R-X? ETEA2007
Only nuclephile ( CN- , Br- , I- , HS- ) They always give nucleophilic substitution reaction
Question#7
Among the alkyl halides, which always follows SN2 mechanism MDCAT2017
Question#8
Which is an intermediate compound in SN1: MDCAT2017
Question#9
Which product is obtained by hydrolysis of 1-chlorobutane with the aqueous sodium hydroxide ? MDCAT2019
Question#10
Alkyl halides involving -C-X Bond breakage and -C-Nu bond formation simultaneously would follow the mechanism: MDCAT2020
Question#11
The alkaline hydrolysis of bromoethane shown below give alcohol as the product \( CH_3-CH_2-Br \rightarrow CH_3-CH_2-OH \)
The reagent and condition used in this reaction may be MDCAT2012
Strong Nuc / Strong base( RO-,OH- ) with 1o Alkyl halide will always give SN2
Weak Nuc / Weak Base (H2O, ROH, RCOOH) with 3o Alkyl halide will always give SN1 or E1
Strong base/ bulky base (t-butylO-, Alc.KOH) always give elimination reaction.
Question#12
In substitution reaction, secondary halogenoalkane give/show MDCAT2012
Question#13
If halogenalkanes are mixed with an excess of ethanoic ammonia and heated under pressure amine are formed. Which amine is formed in the following reaction ? MDCAT2014
\( CH_3-CH_2-Br + NH_3 \rightarrow Amine \)
If ammonia is in excess
\( CH_3-CH_2-Br + NH_3 \rightarrow CH_3-CH_2-NH_2 \)
If alkyl halid is in excess
\( CH_3-CH_2-Br + NH_3 \rightarrow CH_3-CH_2-NH-CH_2-CH_3 \)
\( CH_3-CH_2-Br + CH_3-CH_2-NH-CH_2-CH_3 \rightarrow CH_3-CH_2-N<_{CH_2-CH_3}^{CH_2-CH_3} \)
\( CH_3-CH_2-Br + CH_3-CH_2-N<_{CH_2-CH_3}^{CH_2-CH_3} \rightarrow [_{CH_3-CH_2}^{CH_3-CH_2} >N<_{CH_2-CH_3}^{CH_2-CH_3}]^+Br^- \)
Question#14
During the SN1 reaction , the fast reaction involves MDCAT2017
Question#15
During SN2 reaction, configuration of alkyl halide molecule is MDCAT2010